Superculture® Pet Immune:For gut & digestive health
Clinically validated to improve stool consistency and gut microbiome diversity in dogs and cats
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Key Outcomes from 3 Clinical Studies
- Clinically shown to increase gut microbiome Shannon diversity.1,2
- Clinically shown to improve stool quality in just 28 days in dogs.2
- Clinically shown to improve stool quality in just 28 days in cats.3
- Clinically shown to increase increase the abundance of ~4x more beneficial taxa than placebo in the gut microbiome.2
- Clinically shown to reduce Streptococcus, which is associated with poor gut health in cats 3
- Double-blind, placebo-controlled study Superculture® Pet Immune, conducted 11-2024
- Double-blind, placebo-controlled study Superculture® Pet Immune, conducted 05-2025
- Double-blind, placebo-controlled study Superculture® Pet Immune, conducted 10-2025 through 01-2026
How Superculture® Pet Immune Measures Up
Other INgredients
Others
Stool quality improvement in dogs
In 28 days
None, some worsen stool quality
Stool quality improvement in cats
In 28 days
No statistically significant data
Increased gut microbiome diversity in dogs
In 28 days
No statistically significant data
Decreased Streptococcus, a key taxon associated with dysbiosis in cats.
In 28 days
No statistically significant data at relevant dose
The Unmet Health Need
- Digestive and gut health is one of pet parents' biggest concerns.
- Over 90% of pet parents say gut health is a critical need. And in cats specifically, gastrointestinal upset is the leading driver of vet visits.
- Yet, current solutions demonstrate limited efficacy: their effects stay localized in the gut, their mode of action is often unclear, and their results depend heavily on each pet’s individual diet and microbiome.
Our Key Insight
- Indole compounds are uniquely produced by a healthy gut microbiome, circulate systemically throughout the pet’s body, and elicit a wide range of positive health benefits across the gut, skin, and immune system.
- They constitute an important and previously unharnessed modality to support pet health at its root.
Our Development Process
- Through high-throughput screening of our proprietary biobank, we identified microbial strains with exceptional indole metabolism capabilities.
- We optimized the fermentation process to maximize beneficial indole yields while ensuring stability.
- We then validated the ingredient’s efficacy in three double-blinded, placebo-controlled clinical studies, measuring stool quality and gut microbiome composition.
- The result: industry-leading efficacy across stool quality and gut microbiome in just a few weeks in dogs and cats.
Ingredient Composition
Made from natural, non-GMO microbial strains.
Dried Pediococcus acidilactici fermentation product
Covered by AAFCO definitions and included on the EU QPS list See Tech Spec Sheet
Ingredient Labeling Suggestions
The ingredient is often labeled as:
- Dried Pediococcus acidilactici fermentation product
- Postbiotic (Pediococcus acidilactici)
- [Canine/Feline] Immune Health Postbiotic
- [Canine/Feline] Immune Health Fermentate
- [Canine/Feline] Gut Health Postbiotic
- [Canine/Feline] Gut Health Fermentate
Superculture® Pet Immune in Industry Publications
PEER-REVIEWED
A novel postbiotic improves stool consistency in dogs: A randomized, double-blind placebo-controlled study
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PRESENTATION
QC Best Practices for Consistency and Efficacy in Pre-, Post- and Probiotics